Perioperative anaphylaxis: a potential hazard to the safety of surgical patients

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Perioperative anaphylaxis.

BACKGROUND AND OBJECTIVE Anaphylaxis remains one of the potential causes of perioperative death, being generally unanticipated and quickly progress to a life threatening situation. A narrative review of perioperative anaphylaxis is performed. CONTENT The diagnostic tests are primarily to avoid further major events. The mainstays of treatment are adrenaline and intravenous fluids. CONCLUSION...

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Perioperative anaphylaxis.

The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents represent the most frequently involved substances, followed by latex and antibiotics, but every drug or substance used may be involved. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests and specific IgE or basophil activation ass...

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Anaphylaxis during the perioperative period.

Anesthesiologists use a myriad of drugs during the provision of an anesthetic. Many of these drugs have side effects that are dose related, and some lead to severe immune-mediated adverse reactions. Anaphylaxis is the most severe immune-mediated reaction; it generally occurs on reexposure to a specific antigen and requires the release of proinflammatory mediators. Anaphylactoid reactions occur ...

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ژورنال

عنوان ژورنال: Chinese Medical Journal

سال: 2020

ISSN: 0366-6999,2542-5641

DOI: 10.1097/cm9.0000000000000659